Omics and data analysis

Non-targeted approaches: method validation and application

This research area focuses on the development and validation of novel analytical methods, based on chromatography and high-resolution mass spectrometry, for untargeted and omics applications in clinical, environmental and foodstuff fields.

Experimental activities include the analysis of emerging contaminants, both targeted and untargeted, in various environmental compartments (i.e. surface water, groundwater, wastewater, and soil) and biological fluids (plasma, urine, etc), metabolomics of plants, cells and diseases, other targeted and untargeted analysis.

To these aims, the following techniques are employed: liquid chromatography coupled to high-resolution mass spectrometry, ion exchange chromatography coupled to high-resolution mass spectrometry, gas-chromatography coupled to mass spectrometry, head-space gas-chromatography coupled to mass spectrometry.

Unit Coordinator: Prof. Sara Bogialli and Dott. Marco Roverso

Chemosphere 364, 142994 (2024) 

Volatile organic compounds and real-time mass spectrometry

This research area focuses on the development and application of real-time detection techniques for volatile organic compounds (VOCs).

Experimental activities include the development of chemical ionization techniques for real-time mass spectrometry, the analysis of VOCs in several biological systems of interest in plant science, food science and technology, health science, atmospheric science.

To this aims, the following techniques are employed: Proton Transfer Reaction – Mass Spectrometry (PTR-MS), Thermal Desorption – Gas Chromatography – Mass Spectrometry (GC-MS).

Unit Coordinator: Prof. Luca Cappellin

Atmos. Chem. Phys, 19, 3125–3135 (2019)

Current projects