{"id":230,"date":"2025-09-12T13:09:25","date_gmt":"2025-09-12T13:09:25","guid":{"rendered":"https:\/\/research.chimica.unipd.it\/bioorganic-chemistry\/?page_id=230"},"modified":"2025-09-12T13:09:26","modified_gmt":"2025-09-12T13:09:26","slug":"marta","status":"publish","type":"page","link":"https:\/\/research.chimica.unipd.it\/bioorganic-chemistry\/index.php\/marta\/","title":{"rendered":"Marta De Zotti"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"259\" height=\"241\" src=\"https:\/\/research.chimica.unipd.it\/bioorganic-chemistry\/wp-content\/uploads\/2025\/09\/immagine.png\" alt=\"\" class=\"wp-image-231\"\/><\/figure>\n\n\n\n<p>MEMBRANE-ACTIVE PEPTIDES<\/p>\n\n\n\n<p>Aib (alpha-aminoisobutyric acid)-containing peptides are unique in their ability to interact with membranes. Aib is a naturally-occurring, non-coded residue with strong helix-inducing ability, due to the steric hindrance of the two geminal methyl groups on the alpha carbon. The rigid and well-defined helical conformation of Aib-peptides makes them remarkably stable under critical environmental conditions. Aib-peptides are also resistant to proteolysis, thanks to Aib not being easily recognized by proteolytic enzymes. Their features make them ideal candidates for a variety of applications outside the physiological environment<\/p>\n","protected":false},"excerpt":{"rendered":"<p>MEMBRANE-ACTIVE PEPTIDES Aib (alpha-aminoisobutyric acid)-containing peptides are unique in their ability to interact with membranes. Aib is a naturally-occurring, non-coded residue with strong helix-inducing ability, due to the steric hindrance of the two geminal methyl groups on the alpha carbon. The rigid and well-defined helical conformation of Aib-peptides makes them [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-230","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Marta De Zotti - Bio Organic Chemistry<\/title>\n<meta name=\"description\" content=\"Marta does research in Organic Chemistry, Spectroscopy and Biochemistry. 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